Drug Therapy And Weight Loss Improve Vision In Idiopathic Intracranial Hypertension

A national medical trial has discovered that an inexpensive medication, acetazolamide, when coupled with a weight-loss plan, improves vision for patients with idiopathic intracranial hypertension (IIH) who’ve mild visual reduction. The trial was funded by the National Eye Institute, part of the National Institutes of Health (NIH), and was conducted at Emory Eye Center and 27 other sites across the country.

The study wanted to assist with the management of IIH, known as pseudomotor cerebri also, which causes increased pressure around the mind. IIH predominantly impacts women of reproductive age who are also overweight. It is estimated that some 100,000 Americans have IIH, with the quantity rising combined with the proportion of the populace that is overweight.

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Symptoms include headaches and visible problems, including blind places, poor side (peripheral) vision, dual vision, and short-term shows of blindness. Approximately five to 10 percent of women with IIH experience disabling eyesight reduction. Beau Bruce, MD, MS, the main investigator for the trial at Emory Eye Center. Michael Wall, MD, professor of neurology and ophthalmology at the University of Iowa and the study’s trial director.

IIH’s high pressure around the mind can result in swelling and damage of the optic nerves that connect the attention to the brain. A weight-loss of five to 10 percent can assist in improving symptoms. The drug acetazolamide is known to reduce fluid production in the brain, and has been used as an add-on therapy for IIH often. In severe cases, surgical treatments might be used to reduce pressure on the optic nerve. In the study at half a year, participants’ vision on acetazolamide improved by twice as much as those on placebo and the drug seemed to reduce swelling of the optic nerve as well.

The drug-weight reduction combination also resulted in greater improvements in daily function and quality of life compared to weight loss by itself. The trial was funded by the NIH and was coordinated by the Neuro-Ophthalmology Research Disease Investigator Consortium (NORDIC). April 22 in the Journal of the American Medical Association The results were published, and will be presented on, may 2 during the Clinical Trials plenary session of the American Academy of Neurology meeting in Philadelphia.

The trial will observe participants for five years to determine whether they have the ability to maintain a wholesome weight and control their symptoms over the future. The trial is funded by cooperative agreements from NEI (EY017281 and EY017387). Wall M et al. NORDIC IIH Study Group. Effect of Acetazolamide on Visual Function in Patients with Idiopathic Intracranial Hypertension and Mild Visual Loss: The Idiopathic Intracranial Hypertension Treatment Trial.

To see typical American food habits presented such as this just blows me away. They call this the “obesogenic environment”; the theory that we’re surrounded by tasty but harmful food and situations that favor the consumption of it. Strong evidence implies that glycemic index and/or glycemic load are not associated with body weight; thus, it is not necessary to consider these measures when choosing carbohydrate foods and drinks for weight management.

The first problem is the creation of the category “solid extra fat and added sugars”, abbreviated SoFAS. With the creation of this term, they lump pastured butter with Crisco and Red Hots collectively. If they are hiding the evidence that pastured butter, virgin coconut oil, or red palm oil donate to heart disease, I’d like to see it so I can cease eating them! Another nagging problem is their list of suggestions to curb the obesity epidemic. The existing high rates of overweight and obesity among practically all subgroups of the populace in the United States demonstrate that lots of Americans are in calorie imbalance-that is, they consume more calories than they expend.